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For gastroparesis, reglan works by affecting different receptors in the gastrointestinal gi tract, including a dopamine receptor that has a relaxant effect on the gut.

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Reglan Injection may be used to facilitate small bowel intubation in adults and pediatric patients in whom the tube does not pass the pylorus with conventional maneuvers.

Giving a promotility drug such as metoclopramide theoretically could put increased pressure on suture lines following a gut anastomosis or closureThis possibility should be considered and weighed when deciding whether to use metoclopramide or nasogastric suction in the prevention of postoperative nausea and vomiting.

Metoclopramide is excreted in human milkCaution should be exercised when metoclopramide is administered to a nursing mother.

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although reglan works in most of the gi tract, it has little to no effect on the colon.

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